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Correct and consistent condom use is associated with reduced HPV transmission between sexual partners, but less frequent condom use is not (8).

However, because areas not covered by a condom can be infected by the virus (7), condoms are unlikely to provide complete protection against the infection.

All three vaccines are given through a series of three injections into muscle tissue over a 6-month period.

In October 2016, the FDA approved a 2-dose schedule for boys and girls initiating vaccination with Gardasil 9 at ages 9 to 14 years (the second dose is to be administered 6–12 months after the first).

The FDA has approved Gardasil and Gardasil 9 for use in females ages 9 through 26 for the prevention of HPV-caused cervical, vulvar, vaginal, and anal cancers; precancerous cervical, vulvar, vaginal, and anal lesions; and genital warts.

Some HPV infections, however, can persist for many years.

Human papillomaviruses (HPVs) are a group of more than 200 related viruses.

More than 40 HPV types can be easily spread through direct sexual contact, from the skin and mucous membranes of infected people to the skin and mucous membranes of their partners.

Because the infection is so common, most people get HPV infections shortly after becoming sexually active for the first time (13, 14). Someone can have an HPV infection even if they have no symptoms and their only sexual contact with an HPV-infected person happened many years ago.

HPV vaccination can reduce the risk of infection by the HPV types targeted by the vaccine.

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